Alexander Djiku scored the only goal in the 49th minute after Mali’s goalkeeper, Djigui Diarra, could not catch a corner from Jordan Ayew.

Mali needed a win to keep their chances of automatic qualification alive. They controlled the game for the last half hour but could not break through Ghana’s strong defence.

With this victory, Ghana now has 19 points and a three-point lead at the top of Group I with two more matches to play next month.

Otto Addo’s team will play away against the Central African Republic and then host Comoros. A single win in these matches could secure their place in the World Cup for the second time in a row.

In the African qualifying, only the nine group winners are guaranteed a spot in the tournament next year, but the four best-ranked teams can enter the playoffs.

The top-seeded Mali have yet to compete in the World Cup finals and can no longer finish at the top of the group.

Mali are currently in fourth position in the standings, four points behind Madagascar, who are in second place after coming back to defeat Chad 3-1 earlier on Monday.